What makes cells move to repair a wound? how this process is regulated? A new study published in Nature revealed this process.
Cells respond to biomechanical stress
According to the researchers, the process depends on biomechanical stresses between cells. When a wound occurs an empty space is made and the mechanical forces disappear leading the cells produce substances that lead other cells to move towards the empty space.
Cells are organised into leaders and followers
The study showed that the cells are organised into leaders who are fount in the front pack. They express a genetic code for proteins that attract other cells to move towards the wound. The other cerlls are followers, they don't express the protein.
The research can be used to treat diabetic wounds
According to the researchers, these fondings can be helpful for treating diabetic wounds that are diffcult to treat and they ultimately result in amputaion of the limbs.